

Instructor Contact:
Instructor Kathy Blaney Office HPA II 317 Office
HoursTues, Wed, Thurs 9-11am. Phone (407)823-5798 Personal kblaney@mail.ucf.edu

Course Description:Overview of the basic principles of the immune response involving cells tissues and molecules. Antigen – antibody interactions, cell mediated immunity and an introduction to Immunopathology

Course Objectives:Upon completion of this course, students will be expected to:
- State the function of the cells involved in the immune response.
- List and state the function of the tissues and organs in the lymphoid system
- Describe the role of complement and compare the two pathways of activation.
- List and describe the molecules, mediators and cells involved in the inflammatory process.
- Compare and contrast the structure, function and receptors of the immunoglobulins.
- Define the role of the T-cell receptor and the MHC molecule.
- Explain the concept of immunoglobulin diversity.
- Describe the process of antigen recognition by antibodies and T cells.
- Summarize the important regulatory elements in the immune response.
- Define immune tolerance.
- Compare and contrast the immune response to viruses, bacteria, fungi and parasites.
- Describe the various types of vaccinations and compare their effectiveness
- Define immunotherapy and its role in tumor immunology
- Describe the clinical manifestations and causes of immunodeficiency.
- Compare and contrast the 4 main types hypersensitivity reactions with regard to causes and clinical manifestations.
- Summarize the immune mechanisms involved with graft rejection.

Required Text:
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Basic Immunology: Functions and Disorders of the Immune System; Abul K. Abbas and Andrew H. Lichtman, W.B. Saunders, 2001

Optional Material:Course Pack of Lecture notes: Available at the Campus Bookstore ONLY. Lecture notes will NOT BE AVAILABLE ON-LINE
Evaluation:| Test | Description | Weight toward final grade |
|---|---|---|
| TESTS |
6 announced multiple choice exams, one grade will be dropped , each exam is cumulative |
EACH IS 1/5TH OF FINAL GRADE |
| ATTENDANCE | Attendance will be monitored periodically, class attendance may affect final grade |
|

Additional Policies:| Grading and evaluation | The lowest test grade will be dropped |
| Attendance |
ABSOLUTELY NO MAKEUPS FOR ALL EXAMS! Attendance in class may affect grades that are “borderline”; i.e.: raise a grade that is close to a letter cutoff |
| Extra credit | Extra credit is not possible due to the size of the class. |
| Accommodations | Students needing support for disabilities need to let me know and make arrangements BEFORE exams. |
| Academic integrity | Review the code of conduct! Tests will be monitored and students found cheating will be dismissed from class. |
| Academic courtesy | Show consideration for your classmates! Walking in late, leaving early, talking, cell phones, beepers, etc are distracting and demonstrate lack of consideration for others who may want to learn. |

Login and Password InformationTo access the "e-Community" or "Class Login" portions of this course, students must follow UCF's log-in and password conventions.
